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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ASH1L All Species: 15.45
Human Site: S1746 Identified Species: 34
UniProt: Q9NR48 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9NR48 NP_060959.2 2969 332790 S1746 A T A S A P P S S S P G R S H
Chimpanzee Pan troglodytes XP_513861 2964 332149 S1746 A T A S A P P S S S P G R S H
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851926 2974 332800 S1748 A S A S G P P S S S P G H S H
Cat Felis silvestris
Mouse Mus musculus Q99MY8 2958 331289 P1742 I T T V S A P P S S S P G H S
Rat Rattus norvegicus NP_001101159 2918 326454 P1742 I T T V S A P P S S S P G H S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511389 1395 154154 S346 L S P A S A L S E I Q H P K L
Chicken Gallus gallus XP_422858 2954 330578 S1735 A N V S V P P S S S P A R N H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_692254 2962 327377 S1714 S S R Q A S P S T C S S Q P A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VW15 2226 246247 V1177 E I P P E I P V S Q E E I D A
Honey Bee Apis mellifera XP_001122948 2180 246181 S1131 K P Y D E N A S L E E S L E K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784903 3312 363645 E2086 S S S T P N Q E A T T P K R K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 N.A. 94.1 N.A. 91.7 91.2 N.A. 21.5 79.9 N.A. 40.9 N.A. 26.1 26 N.A. 27.3
Protein Similarity: 100 99.6 N.A. 97 N.A. 95.3 94.4 N.A. 31.8 89.2 N.A. 53 N.A. 42.2 43.9 N.A. 43.3
P-Site Identity: 100 100 N.A. 80 N.A. 26.6 26.6 N.A. 6.6 66.6 N.A. 20 N.A. 13.3 6.6 N.A. 0
P-Site Similarity: 100 100 N.A. 86.6 N.A. 33.3 33.3 N.A. 26.6 73.3 N.A. 46.6 N.A. 13.3 6.6 N.A. 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 37 0 28 10 28 28 10 0 10 0 0 10 0 0 19 % A
% Cys: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 0 19 0 0 10 10 10 19 10 0 10 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 0 0 0 0 0 0 28 19 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 10 10 19 37 % H
% Ile: 19 10 0 0 0 10 0 0 0 10 0 0 10 0 0 % I
% Lys: 10 0 0 0 0 0 0 0 0 0 0 0 10 10 19 % K
% Leu: 10 0 0 0 0 0 10 0 10 0 0 0 10 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 0 19 0 0 0 0 0 0 0 10 0 % N
% Pro: 0 10 19 10 10 37 73 19 0 0 37 28 10 10 0 % P
% Gln: 0 0 0 10 0 0 10 0 0 10 10 0 10 0 0 % Q
% Arg: 0 0 10 0 0 0 0 0 0 0 0 0 28 10 0 % R
% Ser: 19 37 10 37 28 10 0 64 64 55 28 19 0 28 19 % S
% Thr: 0 37 19 10 0 0 0 0 10 10 10 0 0 0 0 % T
% Val: 0 0 10 19 10 0 0 10 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _